CGIAR Antimicrobial Resistance Hub
The CGIAR Antimicrobial Resistance Hub, led by the International Livestock Research Institute (ILRI), applies a One Health approach to support the efforts of low- and middle-income countries in controlling agriculture-associated antimicrobial resistance risks, through promoting and facilitating transdisciplinary partnerships. The hub contributes to ILRI's Animal and Human Health program.
In line with the CGIAR antimicrobial resistance strategy that recognizes the need for evidence on links between agriculture and public health outcomes, the CGIAR Antimicrobial Resistance Hub develops evidence-based solutions that are locally relevant and applicable, while being adaptable to other contexts. Research on how to best implement and scale workable solutions is embedded in capacity development activities and supported through advocacy for enabling policies. This research needs effective partnerships across disciplines, which are at the heart of the hub's activities.
Antimicrobial resistance is a global concern which has motivated the mobilization of scientists, international agencies, governmental institutions and relevant stakeholders to reduce antimicrobial use and minimizing the selective pressure for resistant microorganisms as a consequence of indiscriminate use of antimicrobials. It is a complex issue that requires the understanding of social, economic and political factors as much as biological ones. The World Bank estimates a reduction of 3.8% of Gross Domestic Product by 2050 as a result of antimicrobial resistance, especially affecting low- and middle-income countries.
The key function of the CGIAR Antimicrobial Resistance Hub is to convene different stakeholders with interest in antimicrobial resistance research to influence the development agenda. This is achieved by providing an environment that enables collaboration, facilitates the establishment of new research partnerships, and streamlines communications around agricultural-associated antimicrobial resistance to support evidence-based discussions.
The hub underpins the implementation of the CGIAR antimicrobial resistance strategy, which is aligned with efforts of the World Health Organization, the Food and Agriculture Organization of the United Nations, the World Organisation for Animal Health and the United Nations Environment Programme. The strategy comprises research and development activities in five areas to ensure impact in reducing antimicrobial resistance:
- understanding knowledge, attitudes and practices for antimicrobial use or reduction in use and the role of formal and informal markets;
- undertaking research on antimicrobial resistance transmission dynamics at the human-animal-environmental interface in different livestock and aquaculture systems;
- designing and evaluating interventions and incentives to reduce antimicrobials or use them more effectively;
- supporting evidence-based policy dialogue for antimicrobial surveillance and intervention strategies; and
- developing capacity and guiding the scaling of solutions.
CGIAR is well positioned to tackle agriculture-related antimicrobial resistance risks and their implications for human health in low- and middle-income countries. Through the CGIAR Research Program on Agriculture for Nutrition and Health (led by the International Food Policy Research Institute), the CGIAR Research Program on Livestock (led by ILRI) and the CGIAR Research Program on Fish (led by WorldFish), researchers at CGIAR develop activities to understand, improve and design innovative strategies to tackle antimicrobial resistance in low- and middle-income countries. Further, involvement of the International Water Management Institute allows environmental and water system challenges in antimicrobial resistance to be addressed more holistically.
The CGIAR Research Program on Agriculture for Nutrition and Health has a research partnership with the London School of Hygiene and Tropical Medicine which ensures that public health perspectives are included in all research stages, enabling a One Health framework as endorsed by the United Nations and the World Health Organization in 2016. Further, opportunities have arisen through collaboration with new partners.
The CGIAR Antimicrobial Resistance Hub contributes to achieving the Sustainable Developments Goals (SDGs) adopted by the United Nations, supporting global efforts to attain SDGs 1 (No Poverty), 2 (Zero Hunger), 3 (Good Health and Well-being), 5 (Gender Equality), 6 (Clean Water and Sanitation), 8 (Decent Work and Economic Growth), 12 (Responsible Consumption and Production) and 17 (Partnerships for the Goals).
Purpose of the CGIAR Antimicrobial Resistance hub
- Convene stakeholders on antimicrobial resistance to discuss solutions and manage partnerships
- Provide evidence and support for antimicrobial resistance advocacy and policymaking to national partners
- Build a meaningful and impactful research portfolio that sustainably mitigates antimicrobial resistance risks in agriculture, aquaculture and agri-food systems
- Provide a state-of-the-art technical platform for microbiological analysis, antimicrobial resistance tests and residue testing
- Assess policies, incentives, regulations and practices that effectively reduce excessive use of antimicrobials
- Provide a cross-institutional set-up for coordinated antimicrobial resistance research and development activities, e.g. serve countries in facilitating new partnerships and provide space to host visiting scientists.
- Host and maintain an online antimicrobial resistance information platform and long-term biobank
- Run a data storage platform for CGIAR projects on antimicrobial resistance
- Organize training courses on antimicrobial resistance for CGIAR and national partner institutions