The vision of the International Livestock Research Institute (ILRI) is to improve food and nutritional security and to reduce poverty in developing countries through research for efficient, safe and sustainable use of livestock—ensuring better lives through livestock. It is renewing its commitment to better lives through livestock by expanding its activities in East and Southeast Asia. This region’s major socioeconomic transformations—rapid urbanization, market growth, changing diets and increasing incomes—are contributing to rising demand for meat, milk and eggs, the so-called on-going ‘livestock revolution’. In agriculture, there is rapid development of new farming technologies, as well as improvements in crop-livestock production and marketing. But concerns are growing about the threats to natural resources that these changes bring, coupled with growing climate change risk. These agricultural transformations, however, offer opportunities for effecting a more sustainable, equitable, safe and profitable livestock sector. ILRI is committed to working with many partners within and outside the region to support East and Southeast Asia in meeting its goals through research for development in the livestock sector.